Principal Scientific Researcher


Date: Sep 23, 2022
City: San Francisco, CA
Contract type: Full time
The Position

We seek outstanding candidates to join Small Molecule Analytical Chemistry. Responsibilities include characterization of small molecule candidates, method development and qualification, supporting process scale-up and formulation development, release and stability testing of API and drug products.

The successful candidate will develop chiral and achiral HPLC methods, fit-for-purpose spectroscopy methods, conduct assays, document studies in notebooks, summarize and interpret the data, troubleshoot instrument and method problems, present findings at team meetings and contribute to IND/NDA filings.

Youwill accomplish our mission through innovation and teamwork, creative problem-solving, and use of state-of-the-art technology including HPLC, real-time spectroscopic (NIR and Raman) measurements, LC-MS, ultra-high-pressure LC, Prep LC, HSGC, MS (SQ, IT, TOF, LTQ-OrbiTrap), IC, KF, DSC/TGA, UV, and dissolution.

  • BS/MS in a relevant scientific discipline(chemistry preferred) and a minimum
of 2-3 years experience in pharmaceutical industry required.
  • Candidates must have good theoretical knowledge of analytical chemistry,
hands on practical experience on chromatography (HPLC, GC, data handling), vibrational spectroscopy (NIR, Raman and multivariate data analysis) and/or other analytical techniques (MS).
  • Knowledge of current FDA regulations/guidance and strong background in
organic chemistry, pharmaceutics, QC and drug development process are desirable.
  • Candidates should have good problem solving, written and oral communication skills.
  • Outstanding candidates with less relevant industrial or academic experience will beconsidered as Research Associates.
Who we are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated againstCOVID-19 in accordance with customer requirements, the companys health and safety obligations and/or applicable law or guidelines.

Diversity and Inclusion (D&I)are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. Were focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.For more information about equal employment opportunity, visit ourGenentech Careers Homepage.

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