Postdoc Research Associate_Brown Lab - Laurel Springs - job 957461

University of North Carolina at Chapel Hill

Date: 07/22/2021

City: Laurel Springs, North Carolina

Employment type: Full-time

Position Title Postdoc Research Associate_Brown Lab


Vacancy ID PDS003162


Department Pharmacology - 424001


Position Type Postdoctoral Scholar


Salary Range Dependent on Experience


Full-time/Part-time Full Time


If part-time, hours per week


FTE 1.0


Proposed Start Date


Estimated Duration of Appointment 12 Months


Posting Open Date 07/22/2021


Posting Close Date


Open Until Filled Yes


Work Location Chapel Hill, NC


Position Summary
A position is available for a Postdoctoral Research Associate (RA) in the lab of Dr. Nicholas Brown, Department of Pharmacology and the Lineberger Comprehensive Cancer Center. The Brown Lab uses cutting-edge structural biology techniques (e.g., cryo-EM) to understand mechanisms of ubiquitin ligases that drive the cell cycle. Ultimately, these studies will provide fundamental contributions to understanding cell division and therefore cancer.

The RA will read, understand, and successfully execute experiments, as directed and supervised by the P.I. exercising judgment and basic knowledge of biology and chemistry. Necessary preparation will include reading protocols and reading of scientific literature relating to understanding the planned procedures. The individual may be responsible to train new lab members (e.g., rotation students, summer students) on the basic techniques or protocols commonly used in the lab. The RA will maintain an efficient and effective computerized database of protein expression constructs, baculoviruses, and recombinant proteins, reflecting careful and accurate records of all experiments including purpose, methods, and results. Collaborating efforts with other laboratories will be promoted to allow the RA to learn new techniques.


Educational Requirements
PhD in Biochemistry, Pharmacology, or related field is required.




Qualifications and Experience
Must have hands-on experience with recombinant protein purification and AKTA (or related) systems.

Must be able to complete several different tasks simultaneously and have excellent time management skills.

Must have a strong record of reliability, consistency, and organization as demonstrated in written and computer formats.

Must have good interpersonal skills, ability to follow directions, handle criticism, and to work productively with others and independently.


Preference will be given to candidates with experience in ubiquitination, enzymology, protein interaction analyses, and/or structural biology techniques.

Ideal candidates will have experience with recombinant protein expression from baculovirus-infected insect cells and/or cryo-EM.




Equal Opportunity Employer
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.


Special Instructions
For information on UNC Postdoctoral Benefits and Services click here



Quick Link https://unc.peopleadmin.com/postings/196105


Special Physical and Mental Requirements


Department Contact Name and Title Eileen McElhinney, HR Consultant


Department Contact Telephone or Email eileen_mcelhinney@med.unc.edu


Postdoctoral Affairs




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