Associate Scientist, Enzymology DMPK - Groton - job 635648


Date: 02/23/2021

City: Groton, Massachusetts

Employment type: Full-time

Role Summary

Pfizer is seeking a qualified scientist for an Associate Scientist position contributing to ADME (absorption, disposition, metabolism and excretion) sciences in the in vitro enzymology and preclinical pharmacokinetics (PK) group.

The individual will be joining a dynamic group in ADME Sciences Enzymology, Department of Medicine Design, in support of the global Pfizer small molecule research and development portfolio. The position will be responsible for designing and/or conducting ADME enzymology and PK studies in drug discovery and development. The individual will have the unique opportunity to work with project representatives and influence the selection of candidate molecules for drug development.

The scientist will work closely with his/her supervisor to conduct in vitro enzyme kinetic or inhibition studies, enzyme phenotyping, drug metabolism studies, coordinate PK submissions, generate research reports suitable for regulatory submission, and conduct and ensure data quality control (QC). These duties also require the authoring of scientific documents for internal study reports, contributing to external publications, and for reports in support of regulatory submissions.

Role Responsibilities

  • The scientist is expected to conduct in vitro enzymology or ADME experiments and coordinate in vivo pharmacokinetic studies with the coaching and supervision of his/her supervisor or colleagues.

  • The scientist is responsible for generating high quality data in a timely manner, reviewing and uploading data into databases, writing reports, and data QC.

  • The role also involves close collaborations with other scientists in the ADME Sciences group to enable drug discovery or development portfolio support, trouble-shooting, and technology improvement or development.

  • The scientist must be an agile learner and become proficient in utilizing internal software for data management as the recording of data via computer systems is critical and mandatory to adhering to laboratory standard operating procedures.

Basic Qualifications

  • BS/MS degree in chemistry, biochemistry, biology, biomedical, pharmaceutical sciences or related field.

  • Effective verbal and written communication.

  • Ability to work effectively in a team environment.

Preferred Qualifications

  • Demonstrated laboratory experience.

  • ADME/DMPK knowledge, cell culture experience or LC-MS operational experience is useful.

  • Proficiency in the use of Microsoft Office Suite of tools (Outlook, Word, Excel, etc.).

Physical Position Requirements

  • The position will require the scientist to work in the laboratory, including standing, walking, sitting, and lifting solvents.

  • Some travel (a few times per year) may be required to other Pfizer sites or to attend and present at scientific conferences.

Other Job Details:

  • Last Date to Apply for Job: March 22, 2021

  • Eligible for Employee Referral Bonus: YES

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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